منابع مشابه
piRNAs meet mitochondria.
zuc/MitoPLD encodes a conserved enzyme that localizes to mitochondria and hydrolyzes the mitochondria-specific lipid cardiolipin. Surprisingly, zuc/MitoPLD activity is required for Piwi-interacting RNA (piRNA)-mediated silencing of transposable elements in fly and mouse germlines, suggesting that signaling from mitochondria influences the piRNA pathway.
متن کاملThree toxic gases meet in the mitochondria
The rationale of the study was two-fold: (i) develop a functional synthetic model of the Cytochrome c oxidase (CcO) active site, (ii) use it as a convenient tool to understand or predict the outcome of the reaction of CcO with ligands (physiologically relevant gases and other ligands). At physiological pH and potential, the model catalyzes the 4-electron reduction of oxygen. This model was immo...
متن کاملpiRNAs
What is their conservation status? Although mass-strandings of beaked whales provide a dramatic example of the vulnerability of these species to human activities, sonar exposure is not the only, nor necessarily the most important conservation threat to these large predators. Beaked whales live in areas that are hard to survey and their diving behavior precludes reliable visual counts, leading t...
متن کاملEnergetic and Dynamic: How Mitochondria Meet Neuronal Energy Demands
Mitochondria are the power houses of the cell, but unlike the static structures portrayed in textbooks, they are dynamic organelles that move about the cell to deliver energy to locations in need. These organelles fuse with each other then split apart; some appear anchored and others more free to move around, and when damaged they are engulfed by autophagosomes. Together, these processes-mitoch...
متن کاملA k-mer scheme to predict piRNAs and characterize locust piRNAs
MOTIVATION Identifying piwi-interacting RNAs (piRNAs) of non-model organisms is a difficult and unsolved problem because piRNAs lack conservative secondary structure motifs and sequence homology in different species. RESULTS In this article, a k-mer scheme is proposed to identify piRNA sequences, relying on the training sets from non-piRNA and piRNA sequences of five model species sequenced: ...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2011
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2011.03.003